Ratio Extract

Saffron extract

Main ingredients: saffron acid, saffron, safflower aldehyde, etc.
Specifications 4: 1 ~ 20: 1
Appearance: maroon powder
Test method: HPLC
INQUIRY

The efficacy and function of saffron extract:
1. Effect on the uterus: The saffron extract has an exciting effect on the isolated and in vivo uterus of mice, guinea pigs, rabbits, dogs and cats.
2. Effect on the circulatory system: The saffron extract can reduce blood pressure in anesthetized dogs and cats, and can maintain it for a long time, and it has an exciting effect on breathing.
3. Anti-tumor effect: Saffron preparations have obvious anti-cancer and anti-cancer capabilities, especially saffron extract (dimethyl saffron acid) against leukemia, ovarian cancer, colon cancer, rhabdomyosarcoma, colon cancer, papillary sarcoma, squamous cell Tumors and soft tissue sarcomas have strong inhibitory effects.
4. Effect on liver and gallbladder: Saffron extract has choleretic effect, and the active ingredients are α-saffron sodium salt and saffron acid ester. Alpha saffron acid can lower cholesterol and increase fat metabolism. It can be combined with traditional Chinese medicines such as hawthorn, cassia cassia, and Alisma for the treatment of fatty liver.
5. Antioxidant effect: Saffron extract, especially saffron, can effectively inhibit the activity of oxygen free radicals and xanthine oxidase, showing antioxidant biological activity.
6. Protect the kidneys: By studying the rat C-BSA nephritis model, it was found that the proteinuria phenomenon in the experimental group was reduced, and the degree of renal pathological damage was reduced. Among them, saffron is mainly through the inhibition of cyclooxygenase and the reduction of prostaglandin synthesis, and recently the renal capillaries are unobstructed, the blood flow is increased, and the role of inflammatory injury repair is promoted. It is suggested that saffron can interfere with the occurrence of kidney inflammation by improving the release of platelets and inflammatory Chemicalbook media.
7. Intervene in arrhythmia: Saffron acid, the active ingredient of saffron extract, has a good effect against ventricular arrhythmia models induced by aconitine, ouabain and calcium chloride, which provides saffron for the treatment of arrhythmia. The experimental basis provides a feasible basis for the further development of saffron as a Chinese medicine preparation against arrhythmia and myocardial ischemia, suggesting that saffron may be called a new type of preventive and health care Chinese medicine for preventing cardiovascular and cerebrovascular diseases.
8. Regulate the immune function: the saffron extract has obvious effects of promoting blood circulation, removing blood stasis, antibacterial and anti-inflammatory, etc., and then enhances the body's endurance, increases the Specification of immune cells, so as to improve the body's immunity, and adjust the body's blood circulation Balance the body's yin and yang.
9. Prevention and treatment of atherosclerosis: Saffron extract has a good effect in regulating blood lipid, lowering blood pressure and then preventing and treating atherosclerosis.
10. Retinal protection: New Zealand white rabbits were used to make an animal model of high intraocular pressure. A certain dose of saffron extract was injected from the ear margin vein once a day, and a high pressure control group was established. The results showed that the number of retinal ganglion cells in the treatment group was significantly higher than that in the high-pressure control group (P <0.05), indicating that the saffron extract can block retinal ganglion cells from ischemia and hypoxia under chronic high intraocular pressure by improving retinal blood circulation (P <0.05). RGC) protects RGC. It is suggested that saffron extract may protect RGC by reducing free radicals in the retina and blocking the damage of free radicals to the membrane structure, subcellular organelles and nucleus of RGC.
11. Saffron ethanol extract (CSE) can prevent the suppression of long-term enhancement effect (LPT) of hippocampus caused by ethanol. In the serrated gyrus of anesthetized mice, CSE (250mg ? kg-1) can also effectively prevent LPT inhibition caused by acetaldehyde without affecting the learning function of mice. The water extract of saffron can significantly inhibit the reproductive toxicity of cisplatin, cyclophosphamide, mitomycin C and urethan, and inhibit the reproductive toxicity. The size has no significant relationship with the dose. This is mainly because the saffron extract significantly reduces the effects of reproductive toxicity on liver glutathione S transferase (GST).

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