Ratio Extract
Long pepper extract
- Main ingredients: containing pepper salty, volatile oil, the main ingredients are syringene and sesamin.
- Specifications 4: 1 ~ 20: 1
- Appearance: brownish yellow powder
- Test method: HPLC
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The efficacy and role of long pepper extract:
1. Impact on cardiovascular system
Long pepper at different doses has very different effects on the myocardial nutritional blood flow in mice. When the dose is 4.4 ～ 13.3g / kg, the myocardial intake of 86Rb decreases with the increase of dose, which is the β-blocker effect; but when the dose is 17.8g / kg, it shows the β-agonist effect. Increase myocardial nutrient blood flow and coronary flow, improve myocardial metabolism. Long pepper volatile oil can improve the hypoxia tolerance of mice under reduced pressure and normal pressure. It can extend the survival time of mice with increased oxygen consumption caused by Isop and hypoxic mice caused by sodium nitrite. It can significantly resist the changes of T wave and slow heart rate caused by posterior pituitary in rabbits. Long pepper can inhibit the contraction of rabbit isolated coronary arteries caused by KCl in a dose-dependent manner.
2. Anti-pathogenic microorganisms
The volatile oil contained in the long pepper has an inhibitory effect on Staphylococcus aureus, Bacillus subtilis, Bacillus cereus, Shigella, Salmonella typhi T and B, S. yolkii, influenza virus, etc.
3. Sedative and anticonvulsant effects
Long-term intraperitoneal injection of long pepper rats can significantly resist pentylenetetrazol-induced convulsions, electrical convulsions, and "audiogenic seizures". After 5 minutes of injection of long pepper, the activity of the mice decreased, and it had a synergistic effect with thiopental sodium, which can resist the inhibitory effects of morphine and pentobarbital sodium on respiration.
4. Effects on cholesterol metabolism
Longum volatile oil unsaponifiable (OPUM) can significantly reduce the Specification of serum TC and liver Ch in endogenous and exogenous hypercholesterolemia mice, and the effect of reducing Ch is proportional to the dose; significantly inhibit the intraperitoneal injection of Triton in mice As TC rises, mice injected with egg yolk emulsion can also significantly increase the activity of serum lecithin cholesterol acyltransferase, showing that long pepper has a lipid-lowering effect, which is related to its promotion of esterification and excretion of Ch.
5. Other functions
Long pepper can inhibit the tension and contractility of the ileum of rabbits and rats. Its ethanol extract has a significant protective effect on experimental gastric ulcers, and also has a significant inhibitory effect on the amount of gastric juice and the total acidity of gastric juice.
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