Ratio Extract

Gastrodia extract

Active ingredient: Gastrodin
Specification: 1.0% gastrodin
Appearance: brownish yellow powder
Test method: UV
INQUIRY

Efficacy and effects of Gastrodia extract:
1. Sedation: Gastrodia decoction, gastrodin and its aglycone, vanillyl alcohol, etc. can reduce spontaneous activity in mice, significantly prolong the sleep time of mice caused by barbiturate sodium or cyclohexylbarbital sodium, and can fight caffeine The central excitement caused.
2. Anti-convulsions: Gastrodin injection, gastrodin and its aglycone, vanillyl alcohol, etc. can significantly antagonize convulsions caused by pentylenetetrazole, prolong the incubation period of convulsions, reduce mortality or increase the amount of convulsions. Gastrodia polysaccharide can resist convulsions caused by pentylenetetrazol or strychnine.
3. Protection of brain nerve cells: Gastrodin can reduce the mortality of mice under low pressure and hypoxia. Neural cell culture experiments in neonatal rat cerebral cortex show that gastrodin can significantly reduce the effect of glutamic acid (excitatory amino acid), reduce glutamate-induced lactate dehydrogenase (LDH) leakage and nerve cell mortality.
4. Anti-vertigo: Oral Gastrodia extract can improve the rotation-induced anorexia symptoms in mice, improve the spatial discrimination ability of mice in the water maze and the percentage of mice that reach the safe area, and can significantly counteract the reduction of the mice's spontaneous activity .
5. Antihypertensive: Gastrodia and gastrodin can lower blood pressure in many animals. Intravenous injection of Gastrodia elata injection, the total peripheral resistance decreased, blood pressure dropped rapidly, lasting more than 1 ~ 1.5h. Intraperitoneal injection or duodenal administration of rats, blood pressure lowering effect lasted for more than 3h.
6. Anti-platelet aggregation, anti-thrombosis: Gastrodia elata in vitro and in vivo experiments have shown that anti-platelet aggregation can reduce the mortality of mice caused by arachidonic acid-induced acute pulmonary thrombosis. Gastrodia can expand the diameter of the mesenteric artery in rats and accelerate blood flow.
7. Anti-inflammatory and analgesic: Gastrodia can inhibit a variety of inflammatory reactions, reduce capillary permeability, and directly fight the inflammation caused by 5-HT and prostaglandin E2. Gastrodia can inhibit various experimental pains.
8. Effect on the heart: Gastrodia has anti-myocardial ischemic effect. Gastrodia elata alcohol extract intravenously can resist myocardial ischemia in rats caused by pituitary. Intravenous injection of Tianma injection can alleviate the pathological changes of ECG after coronary artery left ventricular branch ligation, reduce the level of serum malondialdehyde, and reduce the area of myocardial infarction.
9. Improve memory and delay aging: Gastrodia can improve the learning and memory function of aging rats. Gastrodia elata extract can significantly improve the scopolamine, sodium nitrite and ethanol-induced memory acquisition, consolidation and reproduction barriers in mice. Gastrodin and its aglycone are the main effective ingredients for improving memory.
10. Enhance immune function: Gastrodia polysaccharides can increase the body's non-Specific immunity and Specific immune function, Gastrodia polysaccharides can also promote virus-induced interferon.

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